vSphere 5 software iSCSI cannot route between subnets

I have run into an interesting situation this morning. Take the vSphere software iSCSI initiator with the VMkernel port IPs on subnet A, and try to connect them to an iSCSI target on subnet B. If it is set up correctly, you can see the list of LUNs in the static...

How could this work?

VMware ESXi 4.1U1. Multipathed iSCSI setup to an IBM MD3000 array. iSCSI VMkernel IP addresses were set up the same between two hosts. They should have been different. IPs on host 1: and IPs on host 2: and iSCSI worked 99.999%...

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